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Autoimmune regulator regulates autophagy in THP-1 human monocytes

Liang SHI, Li-Hua HU, Yi-Rong LI

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 336-341 doi: 10.1007/s11684-010-0096-4

Abstract: The autoimmune regulator (AIRE) is a crucial factor for the induction of central tolerance, and mutations

Keywords： autoimmune regulator     autophagy     monocytes     light chain 3 (LC3)    

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The critical importance of epigenetics in autoimmune-related skin diseases

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 43-57 doi: 10.1007/s11684-022-0980-8

Abstract: Autoimmune-related skin diseases are a group of disorders with diverse etiology and pathophysiology involvedGenetics and environmental factors may contribute to the development of these autoimmune disorders.this review, we discuss the most recent findings regarding the function of epigenetic mechanisms in autoimmune-related

Keywords： epigenetics     autoimmune-related skin diseases     DNA methylation     histone modifications     noncoding RNAs    

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Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 187-219 doi: 10.1007/s11684-015-0386-y

Abstract:

Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte-specificAlthough autoimmune hepatitis occurs in childhood, this review focuses on disease in adults.Transplant recipients are at risk for recurrent autoimmune hepatitis in the allograft, and de

Keywords： autoimmune hepatitis     autoantibodies     diagnosis     immunological diseases     drug-induced liver injury     therapy    

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Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 534-548 doi: 10.1007/s11684-022-0953-y

Abstract: Autoimmune hepatitis (AIH) is a severe globally distributed liver disease that could occur at any age

Keywords： autoimmune hepatitis (AIH)     concanavalin A (Con A)     human menstrual blood-derived stem cells (MenSCs)    

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Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 10-19 doi: 10.1007/s11684-015-0388-9

Abstract: suggests that Th17 cells and their signature cytokines have a pivotal role in the pathogenesis of multiple autoimmune-mediatedHere, we summarize recent research progress on Th17 function in the development and pathogenesis of autoimmunemolecule compounds to manipulate Th17 function for potential therapeutic application to treat human autoimmune

Keywords： IL-17     Th17 cells     RORγt     autoimmune diseases     posttranslational modification     inhibitors    

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The Effect of Plant Growth Regulator TA Emulsive Powder on the Yield and Quality of Kelp

Liu Desheng,Zhang Qun

Strategic Study of CAE 2000, Volume 2, Issue 2,   Pages 68-73

Abstract:

At present, the breeding area of kelp in China is about 15000 hectares, and annual yield of dry product is 270 000 tonnes accounting for 50% of the total yield of seaweed in the world. TA emulsive powder can remarkably increase the yield and improve the quality of kelp. After the kelp seedling soaked in 2 mg/L TA solution for 2 hours and then put into breeding, the growth of rhizoid can be promoted and the seedling preservation rate can be raised, the content of chlorophyll and fucoxanthin increased, photosynthesis rate raised, accumulation of dry substance increased, activity of PEP carboxylase raised, metabolism of carbon promoted, activity of nitric-reductase raised, metabolism of nitrogen promoted, absorption of nitrogen, phosporous, potassium increased, growth and development promoted, contents of nucleic acid and protein raised, physiological adjusmtent strengthened, anti-disease property strengthened, rate of incidence of disease reduced. The yield of dry substance increased by 6.5 t per hectar in average compated with the treatment on the blank, that is increased by 35% . At the sametime, 24.24 kg iodine, 1.665t brown alg gum, and 1.278 t mannitol in kelp are increased per hectar. TA emulsive powder is a pioneer product at home and abroad. It has the advantages of non-toxic, high efficiency, low cost, no deterioration and convenience in storage and transport, etc. It has been popularized in 15 000 hectares in the whole country and the economic benefit is more than 300 million yuan.

Keywords： triacontanol     kelp     plant growth regulator    

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Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 25-30 doi: 10.1007/s11684-013-0244-8

Abstract:

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family. It actually functions as endocrine hormones but does not regulate cell growth and differentiation. It is demonstrated that FGF21 acts on multiple tissue to coordinate carbohydrate and lipid metabolism, including enhancing insulin sensitivity, decreasing triglyceride concentrations, causing weight loss, ameliorating obesity-associated hyperglycemia and hyperlipidemia. Moreover, FGF21 also plays important roles in some physiological processes, such as fasting and feeding, growth hormone axis and thermogenic function of brown adipose tissue. Clinical relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21 in metabolic disease remain to be determined. Both the pharmacological actions and physiological roles make FGF21 attractive drug candidates for treating metabolic disease, but some questions remain to be answered. This article concentrates on recent advances in our understanding of FGF21.

Keywords： FGF21     metabolism     pharmacology     physiology     clinical relevance    

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Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 243-247 doi: 10.1007/s11684-012-0201-y

Abstract: Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes.Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.

Keywords： LADA     diagnostic criteria     autoantibodies     insulin independence     age of diagnosis    

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A linear quadratic regulator control of a stand-alone PEM fuel cell power plant

Amar BENAISSA, Boualaga RABHI, Ammar MOUSSI, Dahmani AISSA

Frontiers in Energy 2014, Volume 8, Issue 1,   Pages 62-72 doi: 10.1007/s11708-013-0291-5

Abstract: This paper introduces a technique based on linear quadratic regulator (LQR) to control the output voltage

Keywords： modeling of proton exchange membrane fuel cell (PEMFC)     controlling of PEMFC     linear quadratic regulator    

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THE ANTHOCYANIN BIOSYNTHETIC REGULATOR MDMYB1 POSITIVELY REGULATES ASCORBIC ACID BIOSYNTHESIS IN APPLE

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: Further studies showed that the anthocyanin biosynthetic regulator MdMYB1 directly activates the expression
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THE ANTHOCYANIN BIOSYNTHETIC REGULATOR MDMYB1 POSITIVELY REGULATES ASCORBIC ACID BIOSYNTHESIS IN APPLE

Jianping AN, Xiaofei WANG, Chunxiang YOU, Yujin HAO

Frontiers of Agricultural Science and Engineering   Pages 231-235 doi: 10.15302/J-FASE-2020367

Abstract: Further studies showed that the anthocyanin biosynthetic regulator MdMYB1 directly activates the expression

Keywords： anthocyanin     apples     ascorbic acid     MdMYB1     vitamin C    

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γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: γδ T cells play important roles in liver infection, non-alcoholic fatty liver disease, autoimmune

Keywords： γδT cells     liver infection     non-alcoholic fatty liver disease     autoimmune hepatitis     liver fibrosis and cirrhosis    

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Effect of Plant Growth Regulator Triacontanol (TA) on the Yield of Rice

Liu Desheng,Lu Xiumin,He Mingzhong,Xiao Huashan,Fan Xiuzhen

Strategic Study of CAE 2002, Volume 4, Issue 11,   Pages 82-88

Abstract:

Triacontanol (TA) emulsive powder is a kind of widespread plant growth regulator.

Keywords： Triacontanol     rice     plant growth regulator    

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Pathogenesis, diagnosis, and treatment of recurrent spontaneous abortion with immune type

Qi-De LIN, Li-Hua QIU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 275-279 doi: 10.1007/s11684-010-0101-y

Abstract: The pathogenesis of autoimmune RSA was mainly associated with antiphospholipid antibody (APA), whileanticardiolipin (ACL or ACA) + anti-β2-GP1 antibody combining multiple assays for effective diagnosis of RSA with autoimmune

Keywords： spontaneous abortion     recurrent     autoimmune     alloimmune     pathogenesis     diagnosis     immunotherapy    

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: Natural killer T cells play important roles in infections, tumors, autoimmune diseases, and metabolicbiology of natural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmune

Keywords： natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholic    

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Title Author Date Type Operation

Autoimmune regulator regulates autophagy in THP-1 human monocytes

Liang SHI, Li-Hua HU, Yi-Rong LI

Journal Article

The critical importance of epigenetics in autoimmune-related skin diseases

Journal Article

Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Journal Article

Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Journal Article

Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Journal Article

The Effect of Plant Growth Regulator TA Emulsive Powder on the Yield and Quality of Kelp

Liu Desheng,Zhang Qun

Journal Article

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Journal Article

Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Journal Article

A linear quadratic regulator control of a stand-alone PEM fuel cell power plant

Amar BENAISSA, Boualaga RABHI, Ammar MOUSSI, Dahmani AISSA

Journal Article

THE ANTHOCYANIN BIOSYNTHETIC REGULATOR MDMYB1 POSITIVELY REGULATES ASCORBIC ACID BIOSYNTHESIS IN APPLE

Journal Article

THE ANTHOCYANIN BIOSYNTHETIC REGULATOR MDMYB1 POSITIVELY REGULATES ASCORBIC ACID BIOSYNTHESIS IN APPLE

Jianping AN, Xiaofei WANG, Chunxiang YOU, Yujin HAO

Journal Article

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Journal Article

Effect of Plant Growth Regulator Triacontanol (TA) on the Yield of Rice

Liu Desheng,Lu Xiumin,He Mingzhong,Xiao Huashan,Fan Xiuzhen

Journal Article

Pathogenesis, diagnosis, and treatment of recurrent spontaneous abortion with immune type

Qi-De LIN, Li-Hua QIU

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article